As people worked with the chemical, they noticed that if they spilled a bit of DMSO on their hands a distinct garlicky taste would be on their tongue shortly thereafter. This intrigued chemists, who began researching how the liquid could so quickly pass through skin and mucosa, but the work was generally limited to exploring non-medical applications. By , however, the FDA closed down clinical trials citing safety concerns. Since then, DMSO has been approved for some specific applications.
In human medicine, these include use as an organ preservative and as treatment for a bladder disease called interstitial cystitis. In it was approved for topical use in horses and dogs. Unlike bute, however, DMSO controls inflammation primarily by acting as an antioxidant. You may be more familiar with anti-oxidant sources in nutrition, such as vitamin E or lycopene, but DMSO has a molecular structure that allows it to function in the same way.
These free radicals are often the byproduct of inflammation and, in turn, cause more swelling and inflammation as they accumulate. DMSO is a free radical scavenger that slows or halts this process. When used to control inflammation in strains and other soft-tissue injuries, DMSO is usually applied topically.
However, it may also be injected into a target area when an injury occurs in particularly dense tissue, such as a bowed tendon, or the site is difficult to reach. A veterinarian may administer DMSO orally or intravenously in the early stages of laminitis to try to slow or halt the inflammatory cascade. DMSO may be injected into a target area when an injury occurs in particularly dense tissue, such as a bowed tendon.
DMSO is a hygroscopic compound, meaning it attracts water. This property makes the compound especially versatile. DMSO can also reduce swelling in the brain and spinal cord, which can be literally lifesaving in diseases like West Nile encephalitis. DMSO may be used to draw fluids out of the lungs in cases of acute pulmonary edema.
Because it pulls water from tissues, DMSO has a diuretic effect, meaning it makes a horse urinate more. This can help flush toxins from the body more quickly. With this action in mind, DMSO is often given intravenously in the treatment of cantharidin poisoning blister beetle toxicity , to lessen the effect of the toxin on the kidneys and intestinal tract.
After episodes of tying up, DMSO may help horses eliminate waste products of muscle breakdown through their urine more quickly. The diuretic action of DMSO, however, can make it unsafe for horses who are dehydrated or in shock. It can further dehydrate these animals or dangerously lower their blood pressure.
For instance, treating rainrot or other skin infections can be difficult because the responsible organisms are buried deep under the skin or crusty, painful scabs. However, a mixture combining antibacterial medication with DMSO can pass through the skin and reach the affected area. For the same reason, DMSO is often added to antifungal medications for treatment of eye conditions and sometimes to steroids for targeted, topical anti-inflammatory treatment.
Likewise, avoid mixing DMSO with substances that could be toxic if ingested, such as organophosphates or mercury salt. Research shows that DMSO slows or blocks conduction of impulses along nerve cells, which in effect reduces pain from musculoskeletal injuries, postoperative incisions and other sources. For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings.
We hope this provides you with a helpful resource to make informed decisions towards your health and well-being. For a supplement, little scientific support. DMSO , or dimethyl sulfoxide, has a long history as a topical anti-inflammatory agent. Certain precautions must be taken when applying DMSO, and it should only be used under the guidance of a qualified healthcare professional. The use of dimethyl sulfoxide DMSO for therapeutic applications is controversial in part because some claims made by advocates appear to extend beyond current scientific evidence, and in part because topical use greatly increases the absorption of any substance that happens to be on the skin, including molecules that are toxic to the body.
Nonetheless, there is some preliminary evidence that when applied to the skin, it has anti-inflammatory properties and alleviates pain, such as that associated with RA. DMSO appears to reduce pain by inhibiting the transmission of pain messages by nerves. It comes in different strengths and degrees of purity, and certain precautions must be taken when applying DMSO.
For these reasons, DMSO should be used only under the supervision of a doctor. DMSO applied to the affected area may reduce pain by inhibiting transmission of pain messages, and may also soften the abnormal connective tissue associated with disorders such as Dupuytren's contracture, keloids, Peyronie's disease, and scleroderma.
Research on the use of topical DMSO to treat Dupuytren's contracture remains preliminary and unproven. Oral supplementation with dimethyl sulfoxide DMSO reduced relapse rates for peptic ulcer significantly better than did placebo or the ulcer drug cimetidine Tagamet in one study. Previous research showed that DMSO in combination with cimetidine was more effective than cimetidine alone. These trials used mg of DMSO taken four times per day.
The authors of these trials believe the antioxidant activity of DMSO may have a protective effect. Oral supplementation with DMSO should not be attempted without the supervision of a doctor. The use of DMSO , a colorless, oily liquid primarily used as an industrial solvent, for therapeutic applications is controversial. However, some evidence indicates that dilutions, when applied directly to the skin, have anti-inflammatory properties and inhibit the transmission of pain messages by nerves, and in this way might ease the pain of minor injuries such as sprains and strains.
However no controlled research exists to confirm these effects in sprains and strains. DMSO comes in different strengths and different degrees of purity.
In addition, certain precautions must be taken when applying DMSO. For those reasons, DMSO should be used only with the supervision of a doctor.
DMSO is not indicated for healthy people. Those who do use this substance should consult a doctor familiar with its use. They can help you understand the potential benefits and risks. Understand how comfrey heals the skin ». Cystitis is inflammation of the bladder. Most often it is caused by a bacterial infection known as a urinary tract infection UTI. This is an overview of star fruit and its nutritional properties.
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Medically reviewed by Judith Marcin, M.
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